Initial hypothesis framing from key intelligence and information assimilation based on data, leads from a novel suggestion to an effective proposition

Developing high confidence 3D model in the absence of accurate structural information by applying algorithms best suited for each case

In-depth comparison study of the catalytic mechanism of the enzyme to lay the foundation for a robust enzyme development strategy

Discovery of key functional residues engaged in substrate binding; transition-state stabilization; product release and estimating their mutability for enzyme engineering

Creation of a focused library of variants with optimised functional hotspots and in depth study of hundreds of variants designed to elucidate desired activity